Activin A: An Alpha in the TGF Beta Family
Activin A is a member of the TGF-beta superfamily of cytokines and is involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
Differentiate stem cells into endoderm or mesoderm cells
Transcription factor involded in many biological processes: Tissue morphogenesis, fibrosis, inflammation, hematopoiesis and stem cell differentiation.
Activin A is mainly used for stem cell cultivation in order to differentiate the stem cell into endoderm or mesoderm.